Life Science Mini-Challenges

Mini-Challenges are short, auto-graded science activities that give students checks for understanding with immediate feedback.
Add any Life Science Mini-Challenge to your LMS in just a few clicks. Open an activity, scroll to the bottom, and use Embed (Canvas or Schoology) or copy and paste the URL link (Google Classroom). Students may retry until successful, then submit a screenshot of their score for credit.

Google Form: Suggest a Mini-Challenge Topic or Activity

Scientific and Engineering Practices

Nature of Science

Sort

Not vs. Nature of Science Sort

Nature of Science

4 Questions

Nature of Science

Jane Goodall: Nature of Science & 4 Questions

Jane Goodall Nature of Science Questions

Scientific Law vs. Theory

5 Questions

Variables in Bean Sprout

Experiment:  3 Questions

Variables in Photosynthesis

Experiment:  3 Questions

Variables in Osmosis

Experiment:  4 Questions

Osmosis Experiment

Scientific Investigations

Crossword

Cell Theory & Cell Discovery

Cell Theory Vs. NOT 

Sort

Cell Theory Vs. NOT Cell Theory

Cell Theory

5 Questions

Cell Theory 5 Questions

Investigating Cells

5 Questions

Investigating Cells 3 Questions

Cell Structure & Organelles

Plant and Animal Cells

Venn Diagram

Plant Cell Diagram

Drag and Drop

Parts of a Cell Vocab

Drag and Drop

Cells Under the Microscope

Plant Cell

Under Microscope

Plant Cell Under a Microscope

Animals Cell

Under Microscope

Animal Cell Under a Microscope

Cell Division

Phases of Mitosis

Drag and Drop Labels

Phases of Mitosis Diagram Drag Labels

Phases of Mitosis

Drag and Drop Images

Cell Transport & Homeostasis

Osmosis

Drag and Drop

Osmosis Drag and Drop

Osmosis

4 Questions

Simple Diffusion

PhET Sim & 5 Questions

Diffusion Sim and 5 Questions

Biological Organization (Cells → Organism)

Levels of Organization 

Drag and Drop

Levels of Organization Label the Diagram

Unicellular vs. Multicellular

Organisms Sort

Tissue Type

Sort

4 Tissue Types

Small Intestines Tissues

5 Questions

Tissues of the Small Intestine_ 5 Questions

Frog Anatomy Review

No Questions

Frog Internal Anatomy Review (No Questions)

Frog Internal Anatomy

Drag and Drop

Water’s Journey Through

Plants Drag and Drop

Waters Journey Through Plants

Biological Organization (Cells → Organism)

Domain to Species

Put in Order

Put in Order_ Broadest (Domain) to Most Specific (Species)

Kingdom of Eukarya Domain

Sort

Phylum of the Plant Kingdom

Sort

Organize into the Correct Phylum of the Plant Kingdom

Butterfly and

Moth Dichotomous Key

Butterfly and Moth Dichotomous Key

Binomial Name

3 Organisms

Photosynthesis

Photosynthesis Diagram 1

Drag and Drop

Photosynthesis Diagram 2

Drag and Drop

Photosynthesis Diagram 2

Photosynthesis Diagram 3

Drag and Drop

Photosynthesis Reaction_ Drag and Drop Images

Photosynthesis & Plankton

Drag and Drop Labels

Photosynthesis in Phytoplankton_ Drag and Drop Labels

Photosynthesis & Plankton

Drag and Drop Images

Photosynthesis in Phytoplankton_ Drag and Drop Images

Photosynthesis

Cloze

Photosynthesis

Crossword

Photosynthesis Crossword Puzzle

Chlorophyll Concentrations

Graph & 5 Questions

Cellular Respiration

Cellular Respiration

Categorization

Cellular Respiration Categorize

Cellular Respiration

Drag and Drop

Cellular Respiration Reaction_ Drag and Drop ImagesPhotosynthesis and Cellular Respiration Energy Cycle

How Photosynthesis and Cellular Repiration Work Together

Photosynthesis & Cellular

Respiration Work Together

Photosynthesis & Cellular Respiration

Matter Cycling in Ecosystems

Nitrogen Cycle

Drag and Drop

Energy Flow in Ecosystems

Marine Food Chain

Drag and Drop

Marine Food Chain

Marine Energy Pyramid

Drag and Drop

Marine Energy Pyramid

Forest Energy Pyramid

Drag and Drop

Forest Energy Pyramid

Energy Flow in Ecosystems

Drag and Drop

Food Webs: Energy & Matter

Set 1: 5 Questions

Food Web

Food Webs: Energy & Matter

Set 2: 5 Questions

Food Web

Food Webs: Energy & Matter

Set 3: 5 Questions

Food Web

Coming Soon

Physical and Behavioral

Adaptations Sort

Responses to Ecosystem

Changes Sort

Coming Soon

From Cell to Gene

Drag and Drop

From Cell to Gene

Complete the DNA Strand

Drag and Drop

Complete the DNA Strand

Punnett Square: Yy x yy

2-Part Activity

Punett Square Y x Yy

Punnett Square: YY x yy

2-Part Activity

Punnett Squares YY x yy

Punnett Square: Yy x Yy

2-Part Activity

Punnett YY x yy

Natural Selection Set 1

PhET’s Sim & 5 Questions

PhET Natural Selection Sim Activity 1_ 5 Questions

Natural Selection Set 2

PhET’s Sim & 5 Questions

PhET Natural Selection Sim Activity 2_ 5 Questions

Natural Selection Set 3

PhET’s Sim & 5 Questions

PhET Natural Selection Sim Activity 3_ 5 Questions

Natural Selection Set 4

PhET’s Sim & 5 Questions

PhET Natural Selection Sim Activity 4_ 5 Questions

Evolution of the Horse Foot

From Toes to Hooves

From Toes to Hooves_ Evolution of the Horse Foot

Whale Relatives

From Land to Water

Homologous Limbs

Human and Cat

Homologous Limbs_ Human and Cat

Homologous Limbs

Human and Bat

Homologous Limbs_ Human and Bat

Homologous Limbs

Human and Dolphin

Homologous Limbs Human and Dolphin

Note to Biology Teachers (1/27/2026)

We intend to have a page devoted to Biology Mini-Challenges.  We are working hard and will get there….but it will take a few months. 🙂

Macromolecules and Protein Synthesis

Carbs, Lipids, Proteins,

or Nucleic Acids?

Carbs, Lipids, Proteins, or Nucleic Acids

From Building Block

to Cell Structure

From Building Block to Cell Structure

Protein Synthesis:

Put the Steps in Order

Protein Synthesis_ Put the Steps in Order

Protein Synthesis

Label the Diagram

Protein Synthesis_ Label the Diagram

Food Access and Health Outcomes Data Analysis